Assuming you would like help setting up the Project64 emulator and the Glide64 graphics plugin:
First, you need to download and install the latest version of Project64 from here: https://project64.net/download.html
Once Project64 is installed, open the program and click on "File > Open ROM." From there, browse to the location of your desired N64 game ROM and open it.
Next, click on "Options > Configure Controller Plugin." A new window should pop up. In the "Controller Plugin" drop-down menu, select "Glide64." Then, click on "Configure" and make any necessary changes to the graphics settings. Once you're satisfied, click "OK" to close the window.
Now, you should be able to play your game with the Glide64 graphics plugin!