There's no simple answer to this question - it depends on a variety of factors unique to your situation. That said, there are a few things to keep in mind that may help you make your decision.
Shopify is a large and popular platform with a lot of potential for Indie developers. However, because it is so popular, there is a lot of competition among apps. This can make it difficult to stand out and get noticed.
The other thing to consider is the cost of development. Shopify apps tend to be more complex than other types of apps, because they need to integrate with Shopify's platform and API. This can require more time and effort to develop, which can translate into higher costs.
Ultimately, whether or not it is worth it to get into Shopify app development for Indies depends on your specific situation. If you think you have a great app idea that can compete in a crowded marketplace, and you're willing to invest the time and money necessary to develop it, then it could be worth pursuing.