Yes, Xero can integrate with Shopify. Shopify provides a plugin to connect with Xero's accounting software. The integration provides a number of benefits, including the ability to sync orders, customers, and product inventory from Shopify and incorporate them into the Xero ecosystem. Xero also adds convenience for online store owners by automatically importing bank transactions and filing sales tax returns. In addition, the integration calendar helps keep track of invoices and payments due, helping busy entrepreneurs to stay on top of their finances. Overall, the Xero and Shopify integration is powerful and brings a lot of added functionality to the mix.