To disable Picture in Picture mode in Chrome Desktop, follow the steps below:
- Open Chrome on your desktop.
- Click the three-dot icon (Customize and control Google Chrome) in the upper-right corner.
- Go to Settings.
- Scroll down and click Advanced.
- Select System.
- Under the "Picture-in-Picture" section, toggle the switch to Off.
Alternatively, you can go directly to the picture in picture settings page by typing chrome://flags/#enable-picture-in-picture into the address bar, and then changing the setting from “Default” to “Disabled”.
You may need to restart Chrome for the change to take effect.
For more information and helpful tips for using Picture in Picture mode on Chrome desktop, refer to this article: https://www.howtogeek.com/663859/how-to-use-picture-in-picture-in-google-chrome-on-macos-and-windows/